Which substance was used in early insecticides derived from plants?

Nicotine is a well-known natural insecticide that was used historically due to its potent effect on insects. Derived from the tobacco plant, nicotine acts as a neurotoxin, disrupting the nervous system of insects and effectively targeting a wide range of pests. Its efficacy as an insecticide made it a popular choice before the development of synthetic alternatives.

The use of nicotine paved the way for further research into plant-based insecticides, highlighting the importance of natural substances in pest control. Over time, concerns regarding toxicity and environmental impact led to a decline in its use, but it remains a significant example of how substances derived from plants can be employed in pest management.