True or False: Calibration can be done during a trial run on a premeasured area.

Calibration is indeed a critical process to ensure that herbicide applicators are applying the correct amount of product to specific areas. Conducting calibration during a trial run on a premeasured area allows the applicator to assess the equipment's performance under actual operating conditions. By using a predetermined area, the applicator can accurately measure how much herbicide is being applied and make necessary adjustments to the equipment, ensuring optimal application rates.

This method fosters precision and reduces the risk of over-application or under-application, which could lead to ineffective weed control or environmental harm. Furthermore, it provides a practical context in which to verify that the equipment functions correctly and delivers the intended results. Therefore, stating that calibration can be done during a trial run on a premeasured area is true, as it embodies a best practice in the herbicide application process.