The PPE requirements may depend on which factors?

The correct answer highlights the importance of understanding the specific risks associated with herbicide application in relation to personal protective equipment (PPE). Toxicity refers to the potential of a substance to cause harm, and when selecting PPE, it's essential to consider how toxic the herbicide is. Different formulations, such as liquids or granulars, can interact differently with the skin or be inhaled, influencing the type of protective gear needed. Additionally, the route of exposure—whether through skin contact, inhalation, or ingestion—plays a critical role in determining the appropriate PPE.

Given these factors, applicators must assess the nature of the herbicide they are using to ensure they are adequately protected from potential harm. This understanding helps in selecting gloves, masks, protective suits, and other gear that provide the necessary level of safety while handling these chemicals.